Effect of reporting bias on meta-analyses of drug trials

Recently it was discussed that there is only one way to do research perfectly but many ways to do it wrong, especially when a research is done without consideration of bias affecting the study and the implications it may have on any outcomes and reporting (Lakshminarayan, 2016). This is dangerous as it can affect patients and providers whom hear of these studies, and utilize their results to make some health decisions, albeit on false or misleading data. Hart, Lundh & Bero, (2012) discussed that clinical trials are the basis for informed evidence that affects clinical practice, and that reporting bias seems to be most prevalent in drug trials. This is a troubling trend as money seems to having a strong influence on bias in clinical research, drug development especially, as opposed to the health and wellbeing of patients.

 

References:

 

Hart, B., Lundh, A., & Bero, L. (2012). Effect of reporting bias on meta-analyses of drug trials: Reanalysis of meta-analyses. BMJ : British Medical Journal (Online), 344

                  doi:http://dx.doi.org/10.1136/bmj.d7202

 

Lakshminarayan, N. (2016). In how many ways may a health research go wrong?. Journal of The International Clinical Dental Research Organization8(1), 8-13.

 

 

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